Fabrication and characterization of three-dimensional porous cornstarch/n-HAp biocomposite scaffold

Autor: S. F. Khor, C.Y. Beh, Mohd Riza Mohd Roslan, Mohd Jamir Mohd Ridzuan, M.S. Abdul Majid, Kok Yeow You, N. F. Mohd Nasir, Ee Meng Cheng
Rok vydání: 2020
Předmět:
Zdroj: Bulletin of Materials Science. 43
ISSN: 0973-7669
0250-4707
Popis: The aim of this study is to investigate the morphological, functional group, crystallinity and mechanical properties of a three-dimensional porous cornstarch/n-HAp (nano-hydroxyapatite) biocomposite scaffold. In this study, cornstarch/n-HAp scaffolds were fabricated using the solvent casting and particulate leaching technique. The porous cornstarch/n-HAp composites with various cornstarch contents (30, 40, 50, 60, 70, 80 and 90 wt%) were prepared and characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffractometer and compression test. The morphology of the scaffolds possessed macropores (200–600 μm) and micropores (50–100 μm) with a high interconnectivity. The porosity of the porous cornstarch/n-HAp scaffolds varied between 53 and 70% with compressive strength and compressive modulus of 2.03 and 8.27 MPa, respectively. The results suggested that highly porous cornstarch/n-HAp scaffold properties with adequate mechanical properties can be obtained for applications in bone tissue engineering.
Databáze: OpenAIRE