ChemInform Abstract: Thiazole-Derived Potent, Highly Bioavailable Short Duration Growth Hormone Secretagogues

Autor:	Klaus D. Schleim, Tom Jacks, Lihu Yang, Kang Cheng, Greg Morriello, Kwan Leung, Roy G. Smith, Arthur A. Patchett
Rok vydání:	2010
Předmět:	medicine.medical_specialty Chemistry organic chemicals Cell General Medicine Growth hormone Bioavailability Rat Pituitary chemistry.chemical_compound medicine.anatomical_structure Endocrinology Internal medicine medicine Gh release Potency heterocyclic compounds Thiazole Short duration
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199943187
Popis:	Replacement of the phenyl in 3 with a 2-pyridyl or 4-thiazolyl group resulted in increased potency in the rat pituitary cell GH release assay and in beagles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e160a413a05d9adae6de7a6dbb39d997 https://doi.org/10.1002/chin.199943187 Zobrazit plný text záznamu Plný text