Estrogens and Their Analytics by Hyphenated Separation Techniques
Autor: | Bogusław Buszewski, Júlia Ričanyová, Katarína Reiffová, Renata Gadzała-Kopciuch |
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Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Critical Reviews in Analytical Chemistry. 39:13-31 |
ISSN: | 1547-6510 1040-8347 |
DOI: | 10.1080/10408340802569506 |
Popis: | Estrogens as biologically active compounds belong to a group of steroids hormones. The definition of these substances is a very important factor in humans. These compounds play an essential role because regulate many physiological processes, including normal cell growth, development and tissue-specific gene regulation in the reproductive tract and in the central nervous and skeleton systems. The much higher concentration of these matters is key in growth of sexual organs and development of secondary sexual features in women. Synthetic compounds which initiate or enhance the effect of estrogens are called xenobiotics. Xenobiotics are found in the human body in much higher concentrations than are usual. They can modify the functions of the endocrine, reproductive, nervous and immune system. For this reason it is significant to determine these compounds. Their physico-chemical properties and complex structure cause many analytical problems. Chromatography, especially liquid chromatography (LC), is used in an... |
Databáze: | OpenAIRE |
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