Identification of an emulsifier and conditions for preparing stable nanoemulsions containing the antioxidant astaxanthin
| Autor: | Sang Yo Byun, Kim Dm, Chang Ha Lee, Yun P, Hyun Ss |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Aging
food.ingredient Chromatography Antioxidant Chemistry medicine.medical_treatment Pharmaceutical Science Dermatology High-performance liquid chromatography Lecithin Colloid chemistry.chemical_compound Colloid and Surface Chemistry food Chemistry (miscellaneous) Astaxanthin Drug Discovery Emulsion Zeta potential medicine Particle size |
| Zdroj: | International Journal of Cosmetic Science. 34:64-73 |
| ISSN: | 0142-5463 |
| DOI: | 10.1111/j.1468-2494.2011.00682.x |
| Popis: | In this study, oil-in-water nanoemulsions of astaxanthin were prepared by high-pressure homogenization. The influence of emulsifying conditions including emulsifier type, concentration, passing time, astaxanthin concentration and coantioxidants were optimized. The stabilities of nanoemulsions were measured using zetasizer, FF-SEM, TEM, colorimeter and particle size analyzer. The mean diameter of the dispersed particles containing astaxanthin ranged from 160 to 190 nm. The size distribution was unimodal and extended from 100 to 200 nm. The nanoemulsions prepared with glyceryl citrate/lactate/linoleate/oleate (glyceryl ester) had smaller particle size and narrower size distribution than the emulsion prepared with hydrogenated lecithin. Stable incorporation of astaxanthin in nanoemulsion was performed and checked using HPLC, FF-SEM and TEM. The nanoemulsion was not significantly affected during storage under light and thermal condition for one month indicating that the nanoemulsion had a zeta potential of less than -41 mV, indicating a stable colloid. |
| Databáze: | OpenAIRE |
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