Drei-dimensionale computertomographische Auswertung des Mittelgesichtswachstums nach intrauteriner Wiederherstellung von chirurgisch erzeugten Oberkieferdefekten am Schaffetus

Autor: H.-F. Zeilhofer, Nikolaos A. Papadopulos, Edgar Biemer, Julia Henke, P. Böttcher, Laszlo Kovacs, Moschos A. Papadopoulos, Markus Klöppel, Daniel Müller, C. Jannowitz
Rok vydání: 2003
Předmět:
Zdroj: Deutsche Gesellschaft für Chirurgie ISBN: 9783540006596
DOI: 10.1007/978-3-642-19024-7_6
Popis: Aim of this study was to evaluate four different intrauterine methods used for the correction of alveolar cleft-like defects by means of three-dimensional computer-tomographic (3D-CT) analysis in the sheep model. In 12 pregnant sheep an alveolar defect was intrauterine created between the 75th and 95th gestation day. For the closure of the alveolar defect, a bone graft from the iliac crest from the ulna and an implant of collagen-lyophilisate were used. The control group consisted of 4 fetuses. All 16 fetuses were evaluated after euthanasia between the 140th and 145th gestation day by means of CT-scanning of each skull and subsequent 3D reconstruction. Finally, a method of 3D-CT cephalometric analysis was developed. The statistical analysis was performed by means of the SPSS software (level of significance: p < 0.05). The comparison between all operated animals with bone healing and all animals without bone healing revealed no statistical significant differences. When comparing the animals with bone healing with the control group only one variable, and when comparing all operated animals (with or without bone healing) with the control group six variables presented significant differences. According to the results of this study, each of the intrauterine treatment methods used seems not to affect the post-surgical maxillary growth. Nevertheless, a tendency of superior normal growth of the premaxilla can be observed, when bone healing occurs.
Databáze: OpenAIRE