Serum ionized calcium levels may be more closely related to the admission QTc interval than total calcium levels in patients hospitalized with COVID-19

Autor: Önder Bilge, Rojhat Altındağ, Kemal Güneş, Ümit İnci, Murat Çap, Burhan Aslan, Bernas Altıntaş, Ferhat Işık, İlyas Kaya, Ibrahim Halil Tanboga, Abdurrahman Akyüz, Flora Özkalaycı
Rok vydání: 2021
Předmět:
Zdroj: Eastern Journal Of Medicine. 26:433-441
ISSN: 1301-0883
DOI: 10.5505/ejm.2021.69345
Popis: Hypocalcemia prolongs the QTc interval. Total calcium (TCa) measurement can be misleading in cases where the concentration of albumin is abnormal. We aimed to investigate which calcium level —ionized calcium (iCa) or TCa—may be more closely related to the QTc interval in COVID-19 patients in whom hypocalcemia and hypoalbuminemia are observed frequently. Adult patients hospitalized for COVID-19 were included in this study. ICa levels were obtained from the venous blood gas sample examined during the emergency department admission, and the TCa levels were obtained from the biochemistry results on admission. The pH-adjusted iCa (Corrected-iCa) and albumin-adjusted TCa (corrected-TCa) were calculated. The QT interval was measured from the admission ECG and corrected for heart rate using the Bazett formula. Hundred and thirty-two patients were included in the study. The mean age was 50±19 years, and 62 (47%) patients were female. Median iCa level was 1,13 mmol/L (1,08-1,18 interquartile range (IQR)), median TCa level was 2.13 mmol/L (2.02-2.22 IQR). 76 patients (57%) had hypocalcemia (iCa
Databáze: OpenAIRE