Stereoselective synthesis of (−)-tetrahydropyrenophorol

Autor: Reddymasu Sreenivasulu, Bommareddy Pratapareddy, Vuppula Naresh Kumar, Mandava Venkata Basaveswara Rao, Rudraraju Ramesh Raju, Pradeepkumar Thota, Islavathu Hatti
Rok vydání: 2016
Předmět:
Zdroj: Monatshefte für Chemie - Chemical Monthly. 148:751-756
ISSN: 1434-4475
0026-9247
DOI: 10.1007/s00706-016-1754-2
Popis: A simple and efficient synthesis of macrocyclic dilactone tetrahydropyrenophorol has been accomplished from inexpensive and commercially available starting materials. This concise synthesis utilizes regioselective ring opening of epoxide, asymmetric dihydroxylation, and Mitsunobu reaction for the construction of the macrolactone.
Databáze: OpenAIRE