Metabolism of chlorpyrifos by Pseudomonas aeruginosa increases toxicity in adult zebrafish ( Danio rerio )
| Autor: | Sherrice Allen, Hamzah Kharabsheh, Shubo Han, Shirley L. Chao |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
021110 strategic
defence & security studies biology Pseudomonas aeruginosa Pseudomonas 0211 other engineering and technologies Danio Primary metabolite 02 engineering and technology 010501 environmental sciences biology.organism_classification medicine.disease_cause 01 natural sciences Microbiology Biomaterials chemistry.chemical_compound Bioremediation chemistry Chlorpyrifos Toxicity medicine Waste Management and Disposal Zebrafish 0105 earth and related environmental sciences |
| Zdroj: | International Biodeterioration & Biodegradation. 121:114-121 |
| ISSN: | 0964-8305 |
| DOI: | 10.1016/j.ibiod.2017.03.024 |
| Popis: | Chlorpyrifos (CPF) is a commonly used insecticide that has been used on a large scale, resulting in concern about public health and impact on the ecosystem. Bioremediation is one strategy to reduce toxicants in the environment. Toward the goal of reducing toxicants, the present study examined the efficacy of the bacterial species, Pseudomonas aeruginosa, in degrading CPF in freshwater environments. Results showed that after 5 days P. aeruginosa degraded CPF completely to its primary metabolites, CPF-oxon and 3,5,6-trichloro-2-pyridinol (TCP), based on High Performance Liquid Chromatography analysis (HPLC). Compared to control and CPF-only treated groups, mortality increased in zebrafish adults following the addition of P. aeruginosa in water. Our findings suggest that bacterial species such as Pseudomonas aeruginosa do not appear to serve as an optimum bioremediation agent; rather, this species metabolizes CPF to more toxic metabolites, increasing mortality in fish. Chlorpyrifos toxicity usually results from inhibition of acetylcholinesterase; however, the current study did not demonstrate such inhibition as expected. |
| Databáze: | OpenAIRE |
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