Artificial Immunity to Dermacentor Variabilis (Acari: Ixodidae): Vaccination Using Tick Antigens1
Autor: | Daniel E. Sonenshine, Steven B. Ackerman, Mary Floyd |
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Rok vydání: | 1980 |
Předmět: | |
Zdroj: | Journal of Medical Entomology. 17:391-397 |
ISSN: | 1938-2928 0022-2585 |
DOI: | 10.1093/jmedent/17.5.391 |
Popis: | Resistance to adult Dermacentor variabilis was investigated in rats following immunization with extracts derived from whole ticks or tick midguts. Female ticks infesting hosts immunized with midgut extracts demonstrated delayed attachment, reduced engorgement weights, lengthened preoviposition periods, and disturbed egg production compared to ticks fed on nonimmunized control hosts. Also, the percentage hatchability of the eggs from female ticks fed on midgut-immunized hosts was below normal. Similar effects were not noted for ticks fed on hosts immunized with whole tick extracts. The relationship between artificial induction of resistance to ticks via vaccination and acquired resistance sometimes observed in animals repeatedly infested is discussed. |
Databáze: | OpenAIRE |
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