Popis: |
Systemic lupus erythematosus (SLE), an autoimmune disease that affects various organ systems, is common in women of childbearing age. Pregnancy in women with SLE is associated with high maternal and neonatal complications. Maternal complications include increased risk of disease flares, preeclampsia, thrombosis, thrombocytopenia, and maternal death. Fetal complications include neonatal lupus, higher incidence of miscarriages, stillbirths, and neonatal death. The anesthetic management of women with SLE is dependent on the organ involvement and severity of the disease. Epidural analgesia for labor can be performed in parturients who have acceptable platelet counts and coagulation profile. General anesthesia is reserved for patients who have contraindications to neuraxial anesthesia or for emergent cesarean delivery. Endotracheal intubation may be difficult due to cricoarytenoid arthritis, vocal cord palsy, and tracheal stenosis. A multidisciplinary approach in the management can lead to more favorable outcomes. |