| Autor: |
Paul Richards M, Nashra Anjum, Ms. Sharlet, Ms Spoorthy, Paranjothy Kanni, Guddu Shah, B A Viswanath |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Rajiv Gandhi University of Health Sciences Journal of Pharmaceutical Sciences. 11 |
| ISSN: |
2249-2208 |
| DOI: |
10.26463/rjps.11_4_3 |
| Popis: |
Background Antiseptics and disinfectants are mandatory equipment to maintain hygienic environment in hospitals and other health care settings which includes sanitizers preservatives and sporisites. Additol is a preparation in which the main chemical constituents are Terpineol castor oil basil oil propylene glycol and small quantity of liquid caramel made to sufficient quantity of one litre.Objective Castor oil and Sodium hydroxide gives the soap solution and followed by different analytical tests like saponification tests and all the values are validated and these are considered under the jurisdiction of FDA testing guidelines done for the activity and application of disinfectants. Currently during this pandemic it is used in medical settings to stop the spread of viruses.Methodology Castor oil and Sodium hydroxide NaOH were used in the preparation of soap solution. Terpineol oil basil oil propylene glycol and liquid caramel were further used in the preparation.Results The results were in good agreement and were performed under the testing guidelines. Tests were carried out to determine the antimicrobial activity and the obtained results were enclosed by standard limits. By following the standard procedure under the FDA testing guidelines prepared product Additol was compared with marketed product Dettol using Riedel-Walker Co-efficient test and the procured values were within the range.Conclusion The proposed Additol 1000 ml was evaluated for the disinfectant activity following standard procedure. The proposed disinfectant exhibited good disinfectant activity against the test microorganisms. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
