Selective Fluorescence Determination of Amoxicillin Antibiotic Based on Inner Filter Effect of Glutathione-Capped@CdTe Quantum Dots With Cobalt as a Mediating Agent

Autor:	Behzad Rezaei, Fatemeh Hajtaghi Khorasgani, Ali A. Ensafi, Hamid Reza Jamei
Rok vydání:	2019
Předmět:	musculoskeletal diseases Detection limit Materials science Dynamic range Analytical chemistry chemistry.chemical_element Fluorescence Ion chemistry Quantum dot Electrical and Electronic Engineering Selectivity Instrumentation Biosensor Cobalt
Zdroj:	IEEE Sensors Journal. 19:5369-5375
ISSN:	2379-9153 1530-437X
Popis:	Glutathione-capped CdTe quantum dot (GSH-CdTe) is used to determine the trace amount of amoxicillin (AMC) antibiotic. The fluorescence intensity of GSH-CdTe decreased in the presence of Co2+ ions with an increase in AMC concentration. The fluorescent biosensing system is based on the complex formation of AMC with Co2+ ions and its inner filter effect. Several parameters, such as pH, Co2+ concentration, time, and amount of quantum dots affecting the sensor’s sensitivity, were optimized. The linear dynamic range for AMC measurement was 1.0–15.0 ng $\cdot $ mL−1 with a detection limit of 0.2 ng $\cdot $ mL−1 under the optimized conditions. The relative standard deviation for ten repeated determinations of 2.0 and 4.0 ng $\cdot $ mL−1 solutions was 1.4% and 1.5%, respectively. The effect of interfering species on the sensor’s response was studied, and the results show that the proposed method has good selectivity. Finally, the determination of AMC in the blood serums and capsule samples were investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e1164afaa8b13faa0b89c6060b3d9c01 https://doi.org/10.1109/jsen.2019.2905525 Zobrazit plný text záznamu