Effect of gabapentin (neurotonin®) on mood and well-being in patients with epilepsy
| Autor: | Atul C. Pande, Kate R Dimond, Mark W. Pierce, Linda LaMoreaux |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Pharmacology
medicine.medical_specialty Gabapentin business.industry medicine.medical_treatment Placebo medicine.disease law.invention Clinical trial Epilepsy Anticonvulsant Mood Randomized controlled trial Quality of life law Internal medicine Anesthesia medicine business Biological Psychiatry medicine.drug |
| Zdroj: | Progress in Neuro-Psychopharmacology and Biological Psychiatry. 20:407-417 |
| ISSN: | 0278-5846 |
| DOI: | 10.1016/0278-5846(96)00005-x |
| Popis: | 1. Global improvement data from five double-blind clinical trials of gabapentin as add-on therapy in patients with epilepsy were reviewed to assess the effects of gabapentin on mood. 2. One hundred and ninety-four (46%) of 423 gabapentin-treated patients reported improvements in general well-being as compared with 79 (29%) of the 271 placebo-treated patients. 3. Findings support anecdotal reports of improved affective status among patients taking gabapentin and suggest that the study of gabapentin in psychiatric populations may be warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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