Microvascular Haemostasis and the Effect of Local Stimulation and inhibition of Platelet Function. An Experimental Study in Rabbits

Autor:	Bergqvist D, Arfors Ke
Rok vydání:	1976
Předmět:	Stimulation Hematology Heparin Pharmacology Adenosine chemistry.chemical_compound Mesenteric microcirculation Thrombin chemistry medicine Platelet Prostaglandin E1 Laser injury circulatory and respiratory physiology medicine.drug
Zdroj:	Thrombosis and Haemostasis. 36:133-139
ISSN:	2567-689X 0340-6245
Popis:	SummaryThe local stimulation and inhibition of haemostatic plug formation was studied by local infusion and superfusion of different agents – ADP, thrombin, adenosine, heparin, prostaglandin E1 (PGE1) and laser injury. ADP and laser injury shortened venular haemostatic plug formation time whereas adenosine in the superfusate and PGE1 prolonged it. Thrombin infusion had no effect but thrombin in the superfusate significantly stabilised the haemostatic plugs. It is suggested that ADP released from red cells is the most potent stimulator for haemostatic plug formation in the rabbit mesenteric microcirculation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e10c56fdb35364d85499922cd032d528 https://doi.org/10.1055/s-0038-1648017 Zobrazit plný text záznamu