Chemical Purity of Biodegradable Medical-Grade Fibres of Aliphatic Copolyesters
| Autor: | Krystyna Twarowska-Schmidt, Jolanta Jóźwicka, Karolina Gzyra-Jagieła, Danuta Ciechanska, Agnieszka Gutowska |
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| Rok vydání: | 2015 |
| Předmět: |
Aqueous solution
Lactide Materials science Scanning electron microscope Materials Science (miscellaneous) Extraction (chemistry) technology industry and agriculture macromolecular substances Copolyester Industrial and Manufacturing Engineering PLGA chemistry.chemical_compound chemistry Organic chemistry Business and International Management Chemical purity Spinning General Environmental Science Nuclear chemistry |
| Zdroj: | Fibres and Textiles in Eastern Europe. 23:143-149 |
| ISSN: | 1230-3666 |
| DOI: | 10.5604/12303666.1167433 |
| Popis: | Fibres prepared on an experimental scale from biodegradable copolyester of glycolide and lactide (PLGA) and from PLGA with the addition of 9% of atactic poly([R,S]-3-hydroxybutyrate (PLGA+a-PHB) were characterised to assess their possible use in the preparation of surgery sutures. Commercial spinfinish Estesol PF 790 (Bozzetto Group, Italy) was applied on the fibres in the spinning step. A method was prepared for an organic extraction of the spinfinish from the PLGA fibres, and the process efficacy was assessed by scanning electron microscopy (SEM) and by estimating chemical purity. With spinfinish removed, the fibres were subjected to an extraction process which simulated the utilisation of the products in an aqueous medium. The aqueous extracts were analysed to estimate contamination contents. Also estimated was the time in which the fibres degrade when subjected to surplus extrac tion in an aqueous medium. |
| Databáze: | OpenAIRE |
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