| Autor: |
Pereira Tb, Beck-da-Silva L, Balk M, Ramos Vs, Pereira Gb, Giordani L, Schvartzman Pr |
| Rok vydání: |
2021 |
| Předmět: |
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| DOI: |
10.21203/rs.3.rs-174912/v1 |
| Popis: |
Purpose: To ascertain if differences in T1 and T2 mapping exist between ventricular wall segments with and without late gadolinium enhancement (LGE) in patients with myocarditis, and to compare these findings to those of control subjects.Methods: In a case-control design, 22 patients with Cardiac Magnetic Resonance (CMR) evidence of myocarditis and 18 controls with normal CMR were assessed. The workup included: (1) T1 mapping (ShMOLLI); (2) LGE; (3) T2 mapping (SSFP); and (4) the T2 signal intensity of the myocardium divided by that of skeletal muscle (T2 ratio). T1 and T2 mapping of affected (LGE+) and unaffected (LGE-) ventricular segments of cases were compared, as were those of controls versus cases.Results: On within-group comparison, ventricular segments with evidence of late enhancement (LGE+) in cases showed a mean T1 value significantly different from that of unaffected (LGE-) ventricular walls (1057±30 vs. 1028±48; p=0.0001). On between-group comparison, the mean T1 value of LGE- segments in cases was significantly different from the mean of the corresponding walls in controls (1028±48 vs. 996±10; pConclusions: This case-control study suggests that T1 mapping demonstrates significant alterations in the myocardium of patients with myocarditis even in the absence of late gadolinium enhancement. Specifically, T1 mapping revealed diffuse myocardial involvement not evidenced by LGE imaging. T2 mapping was noncontributory. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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