Novel phosphine–phosphites and their use in asymmetric hydrogenation

Autor:	Szabolcs Balogh, László Ürge, Ferenc Darvas, József Bakos, Áron Szöllősy, Gergely Farkas
Rok vydání:	2011
Předmět:	Ligand Organic Chemistry Asymmetric hydrogenation Noyori asymmetric hydrogenation chemistry.chemical_element Substrate (chemistry) Catalysis Rhodium Inorganic Chemistry chemistry.chemical_compound chemistry Molar ratio Organic chemistry Physical and Theoretical Chemistry Phosphine
Zdroj:	Tetrahedron: Asymmetry. 22:2104-2109
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2011.12.007
Popis:	Excellent enantioselectivities and activities have been obtained in the rhodium catalyzed asymmetric hydrogenation of dimethyl itaconate and several dehydroamino acid esters using a new class of BINOL based phosphine–phosphite ligand. The hydrogenation proceeded efficiently even at a substrate/catalyst molar ratio of 10,000 to give the product with 100% conversion and 99.1% enantioselectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e1058a51e875234701ce4af89fca48ba https://doi.org/10.1016/j.tetasy.2011.12.007 Zobrazit plný text záznamu Full Text from ScienceDirect