Lipid and Lipoprotein Responses to Episodic Occupational and Academic Stress
| Autor: | Michael G. Goldstein, Ann L. Saritelli, Raymond Niaura, Peter N. Herbert, Michael J. Follick, Larry Gorkin, Mary M. Flynn, David K. Ahern |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Apolipoprotein B biology business.industry Cholesterol Psychological distress medicine.disease_cause Confidence interval chemistry.chemical_compound Endocrinology chemistry Internal medicine Total cholesterol Plasma lipids Internal Medicine biology.protein Medicine Psychological stress business Lipoprotein |
| Zdroj: | Archives of Internal Medicine. 151:2172 |
| ISSN: | 0003-9926 |
| DOI: | 10.1001/archinte.1991.00400110036008 |
| Popis: | We examined the effects of psychological stress on plasma lipid, lipoprotein, and apolipoprotein levels in three related studies. In the first study, tax accountants (N = 20) and a comparable control group (N = 20) were assessed during and after the tax season. In the second and third studies, first-year medical students (N = 24 and N =16) were assessed at midsemester and immediately before the examinations. Across studies, the stressors induced significant psychological distress. There were no corresponding changes in lipid and lipoprotein levels. Mean stress-induced change in total cholesterol level was -0.04 mmol/L ( — 1.6 mg/dL) (95% confidence interval, —0.23 to 0.16 mmol/L [ — 9 to 6 mg/dL]) for the accountants and 0 mmol/L (0 mg/dL) (95% confidence interval, — 0.16 to 0.21 mmol/L —6 to 8 mg/dL]) and 0.10 mmol/L (4 mg/dL) (95% confidence interval, —0.18 to 0.39 mmol/L [—7 to 15 mg/dL]) for medical students in the second and third studies, respectively. In all studies, change in total cholesterol level correlated with change in total serum protein levels (r=.42 to.60). These results suggest that commonly occurring stressful situations do not produce significant changes in plasma lipid and lipoprotein levels. ( Arch Intern Med . 1991;151:2172-2179) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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