Major prognostic factors in ovarian carcinomas

Autor:	Hannu Haapasalo, N B Atkin, Yrjö Collan
Rok vydání:	1991
Předmět:	Oncology Univariate analysis Prognostic variable medicine.medical_specialty Mitotic index Multivariate analysis business.industry Proportional hazards model Obstetrics and Gynecology Internal medicine Ovarian carcinoma Ascites Medicine medicine.symptom Stage (cooking) business
Zdroj:	International Journal of Gynecologic Cancer. 1:155-162
ISSN:	1525-1438 1048-891X
DOI:	10.1046/j.1525-1438.1991.01040155.x
Popis:	Prognostic variables predictive of survival in ovarian carcinoma were studied in 91 patients with stage I–IV disease. Univariate analysis showed that clinical stage (FIGO), presence of ascites, age of patient, histologic type and grade, cellular DNA content, morphometric grade, mitotic activity index, and volume corrected mitotic index (M/V index) were prognostic. Multivariate analysis using a Cox model showed that the stage (best predictor in total material), the M/V index (best predictor in stage I tumors), the DNA content (best predictor in advanced stages), and ascites were independently prognostic. Morphometry and/or DNA cytometry should be standard in the histo-pathological evaluation of ovarian carcinomas.
Databáze:	OpenAIRE
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