Direct glycosylation with anomeric hydroxy sugars by activation with 3-fluorophthalic anhydride and trifluoromethanesulfonic anhydride

Autor:	Bo-Young Lee, Rita Pal, Kwan Soo Kim, Won-Yong Lee, Ju Yuel Baek
Rok vydání:	2010
Předmět:	Phthalic anhydride animal structures Glycosylation Anomer Trifluoromethanesulfonic anhydride Organic Chemistry macromolecular substances Biochemistry carbohydrates (lipids) chemistry.chemical_compound chemistry Drug Discovery Organic chemistry lipids (amino acids peptides and proteins) Glycosyl
Zdroj:	Tetrahedron Letters. 51:6250-6254
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.09.064
Popis:	An efficient and direct one-pot glycosylation method using anomeric hydroxy sugars as glycosyl donors, employing 3-fluorophthalic anhydride and triflic anhydride as activating agents, has been developed. The present glycosylation utilizing 3-fluorophthalic anhydride resulted in few to no undesired self-condensed esters than the glycosylation using phthalic anhydride. Intermediates in the present glycosylation were identified by an NMR study.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e0d6b1420dd0cf66aaff9b3fc993b843 https://doi.org/10.1016/j.tetlet.2010.09.064 Zobrazit plný text záznamu Full Text from ScienceDirect