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Objectives A relationship between elevated serum uric acid (SUA) and hypertension, metabolic syndrome and cardiovascular disease has been established. In this study, the relationship of SUA levels and anthropometric measures, serum lipid profile and neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) was examined.Methods Anthropometric parameters including body-mass index (BMI), waist circumference (WC), waist to height ratio(WHtR), waist to hip ratio(W/H), waist to pelvic ratio(W/P), neck circumference(NC), body fat mass(BFM) were obtained, and serum lipid profile containing, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol, triglycerides(TG), also, NLP, PLR, basal metabolic rate (BMR), visceral fat level (VFL) and percent body fat (PBF) were measured among 2921 healthy subjects of young and middle-aged Iranian people. Statistical analysis was performed using SPSS 21 software. To assess the normality of data, the Kolmogorov–Smirnov test was used. Logarithmic transformation was performed for some variables with non-normal distribution. The association between 2 quantitative variables was measured using bivariate correlation (Pearson or Spearman). Pearson correlations and multiple regression analysis were performed to assess the correlation between variables. Simple and multiple regression analyses were performed to predict some variables. P- value |