Regioselective Alkoxylation of 2,2,4-Trimethyl-1,3-pentanediol

Autor:	Rahman Mohammad Abdur, Biing-Ming Su, Elliot Isaac Band, Mojahedul Islam
Rok vydání:	2011
Předmět:	Ethylene oxide General Chemical Engineering Regioselectivity Alcohol Alkali metal Medicinal chemistry Surfaces Coatings and Films Catalysis chemistry.chemical_compound Ethoxylation chemistry Organic chemistry Hydroxide Propylene oxide Physical and Theoretical Chemistry
Zdroj:	Journal of Surfactants and Detergents. 14:333-338
ISSN:	1558-9293 1097-3958
Popis:	An efficient procedure for the regioselective synthesis of secondary alcohol alkoxylates from 2,2,4-trimethyl-1,3-pentanediol (TMPD) is described. TMPD was reacted with propylene oxide followed by ethylene oxide in the presence of a catalytic amount of alkali metal hydroxide to form secondary alcohol alkoxylates. Instead of a mixture of compounds resulting from the reaction of TMPD and propylene oxide, the primary hydroxyl group of the TMPD reacted to form predominantly 2,2,4-trimethyl-3-hydroxypentylpropoxylate as the major product. On further ethoxylation the less hindered secondary hydroxyl group of the 2,2,4-trimethyl-3-hydroxypentylpropoxylate reacted predominantly. 13C NMR indicated that the secondary hydroxyl group (96.2 mol%) of TMPD remained unreacted during alkoxylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e0ab4eed67c99b693125f15e15a5f50e https://doi.org/10.1007/s11743-011-1257-4 Zobrazit plný text záznamu Full text from SpringerLink Plný text