| Popis: |
Introduction: Epilepsies are chronic neurological syndromes, characterized by spontaneous and recurrent crises. It is estimated that there is a worldwide prevalence of 1.0% and that around 30% of patients remain refractory to drug treatment. The active Cannabis plant has been used for medicinal purposes. Extracts with a high CBD content have been shown to be effective in reducing the frequency and severity of epileptic seizures. Objective: To expose the therapeutic effects of CBD and its consequences in a patient with crises that are difficult to control. Methodology: Case study. Results: Male patient, 18 years old, has epileptic seizures that are difficult to control since he was 7 months old. Progressively, he presented loss of motor functions, social and environmental interaction, and even with the combination of antiepileptic drugs, the crises remained uncontrolled. Magnetic resonance examinations indicate hypogenesis of the corpus callosum, volumetric reduction of the cerebellar vermis, increase of the cerebrospinal fluid space, posteriorly displaced brain stem, with volumetric loss. The diagnosis suggests Dandy-Walker and West syndrome. In 2017, it started using CBD and currently has an 85% reduction in crises. There was an increase in personal and environmental interaction, improved levels of concentration and bimanual skills, and began to express emotions and feelings more clearly. Conclusion: CBD represents a promising alternative for epileptic refractory patients to drug treatment, which can prevent the occurrence of brain damage and modify the natural history of the disease and the quality of life. |
