Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation

Autor: M. A. Raquin, D. Frappaz, Société Française d’Oncologie Pédiatrique, M. C. Baranzelli, C. Kalifa, C. Patte, E. Bouffet
Rok vydání: 2002
Předmět:
Zdroj: Germ Cell Tumours V ISBN: 9781447132837
DOI: 10.1007/978-1-4471-3281-3_29
Popis: In the SFOP TC-90 and TC-92 protocols, patients with intracranial germinomas and secreting germ cell tumours (sGCT) were treated with a combination of chemotherapy and focal radiotherapy. One chemotherapy cycle included alternating Carboplatin-VP16 and Ifosfamide-VP16. Germinoma patients received two cycles followed by 40 Gy focal radiotherapy, and sGCT three or four cycles followed by focal 55 Gy. Metastatic patients received craniospinal radiotherapy.
Databáze: OpenAIRE