Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation
Autor: | M. A. Raquin, D. Frappaz, Société Française d’Oncologie Pédiatrique, M. C. Baranzelli, C. Kalifa, C. Patte, E. Bouffet |
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Rok vydání: | 2002 |
Předmět: |
Oncology
medicine.medical_specialty Chemotherapy Germinoma business.industry medicine.medical_treatment medicine.disease Carboplatin Craniospinal radiotherapy Radiation therapy Chemotherapy cycle chemistry.chemical_compound medicine.anatomical_structure chemistry Internal medicine medicine Radiology business Germ cell Germ cell tumour |
Zdroj: | Germ Cell Tumours V ISBN: 9781447132837 |
DOI: | 10.1007/978-1-4471-3281-3_29 |
Popis: | In the SFOP TC-90 and TC-92 protocols, patients with intracranial germinomas and secreting germ cell tumours (sGCT) were treated with a combination of chemotherapy and focal radiotherapy. One chemotherapy cycle included alternating Carboplatin-VP16 and Ifosfamide-VP16. Germinoma patients received two cycles followed by 40 Gy focal radiotherapy, and sGCT three or four cycles followed by focal 55 Gy. Metastatic patients received craniospinal radiotherapy. |
Databáze: | OpenAIRE |
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