Synthesis and Characterization of Novel Thiazole Anchored Pyrazolyl Benzoxazoles
| Autor: | B. K. Karale, H. N. Akolkar |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Green chemistry biology Hydrazine Evisa General Chemistry biology.organism_classification Biochemistry Medicinal chemistry Coordination complex chemistry.chemical_compound chemistry GEOBASE FLUIDEX Drug Discovery Polymer chemistry Environmental Chemistry Thiazole Oxazole |
| Zdroj: | Oriental Journal of Chemistry. 31:431-433 |
| ISSN: | 2231-5039 0970-020X |
| DOI: | 10.13005/ojc/310151 |
| Popis: | Formylchromone 1 was treated with 1-(4-(4-bromophenyl)thiazol-2-yl)hydrazine 2 to get (1-(4-(4-bromophenyl)thiazol-2-yl)-1H-pyrazol-4-yl)(2-hydroxyphenyl)methanone --------(3a- e). Compound 3 on treatment with NH2OH/HCl gavethe compound 2-((E)-{1-(4-(4-bromophenyl)- 1,3-thiazol-2-yl)-1H-pyrazol-4-yl}(hydroxyimino)methyl)phenol (4a-e). Compound 4 on treatment with POCl3 gave 2-(1-(4-(4-bromophenyl)thiazol-2-yl)-1H-pyrazol-4-yl)benzo(d)oxazole (5a-e). The synthesized compounds have been characterized with the help of spectral techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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