| Autor: |
Lihui Yuwen, Lianhui Wang, Mei Hu, Haoting Lu |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
2010 3rd International Nanoelectronics Conference (INEC). |
| DOI: |
10.1109/inec.2010.5425164 |
| Popis: |
A simple nanobiosensor based on CdTe/CdS quantum dots (QDs) was designed for the direct determination of glucose with high sensitivity. Herein we demonstrated that the photoluminescence (PL) of CdTe/CdS QDs was sensitive to hydrogen peroxide (H 2 O 2 ). With glucose as substrate and glucose oxidase (GOx) as catalyzer, the product, H 2 O 2 could quench the fluorescence of QDs. Experimental results showed that the decrease of fluorescent intensity was proportional to the concentration of glucose within the range of 1.8µM-1mM under the optimized experimental conditions. In addition, the detection was completed in 96-well plate as an original model of blood sugar detector. A good linear relationship was found within the range of 2mM–30mM. This QDs based sensor for glucose has the potential to be a portable blood sugar detector due to its high sample throughput, short assay time, low sample consumption and reduced overall cost. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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