Photogenotoxicity of Bergamot Oil in Salmonella Typhimurium TA102 and in V79 Chinese Hamster Cells: Efficiency Assessment of Filter Protective Effect

Autor: P. Vic, J. Unkovic, B. Beth, M. Bonnery, D. Gouy, N. Bichet
Rok vydání: 1988
Předmět:
Zdroj: Archives of Toxicology ISBN: 9783540185123
DOI: 10.1007/978-3-642-73113-6_7
Popis: Recently, much attention has been given to the photogenotoxicity of bergamot oil with regard to its potential carcinogenic risk (Zajdela and Bisagni 1981); Cartwright and Walter 1983). Bergamot oil is widely used as a component in cosmetic formulae (sunscreen preparations, perfumes, eaux de toilette). Among its furocoumarin components, 5-methoxypsoralen (5-MOP) is the major photoactive agent (Ashwood-Smith et al. 1980). DNA photoreactivity of 5-MOP has been described in several in vitro biological systems, mainly yeasts (Averbeck et al. 1978) and bacterial and mammalian cell systems (Ashwood-Smith et al. 1982).
Databáze: OpenAIRE