Measurement of Glomerular Filtration Rate by Impulse Synthesis: Clinical Validation and Optimization

Autor: B. Palagi, Angela Broggi, Alessandra Tomasi, Picozzi R, P. Verga, F. Guzzini, C. Cozzi, F. Villa
Rok vydání: 1988
Předmět:
Zdroj: Nuklearmedizin. 27:147-150
ISSN: 2567-6407
0029-5566
DOI: 10.1055/s-0038-1629446
Popis: Impulse synthesis is a technique which relies upon the logic of continuous infusion but extracts the clearance value from single-injection data by shifting and adding them until an asymptotic value is attained. This study has been aimed at validating and optimizing clinically the measurement of glomerular filtration rate by impulse synthesis. A single intravenous injection of 51Cr-EDTA has been made in 32 patients and plasma activity monitored over the next 6 h. Glomerular filtration rate computed by a single-exponential fit method (GFR- SEF) has been shown to be significantly (p
Databáze: OpenAIRE