T3P® mediated domino C(sp2)–H sulfenylation/annulation of enaminones and methylsulfinyls for the synthesis of chromone thioether derivatives
| Autor: | C. Balakrishna, Manoranjan Behera, Satyanarayana Yennam, Venu Kandula, Ramakrishna Gudipati, P. Uma Devi |
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| Rok vydání: | 2019 |
| Předmět: |
Annulation
Regioselectivity 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Ring (chemistry) 01 natural sciences Medicinal chemistry Catalysis Domino 0104 chemical sciences chemistry.chemical_compound Thioether chemistry Chromone Materials Chemistry 0210 nano-technology |
| Zdroj: | New Journal of Chemistry. 43:2458-2463 |
| ISSN: | 1369-9261 1144-0546 |
| Popis: | A new regioselective method for the synthesis of 3-(methylthio)-4H-chromen-4-one and 3-(phenylthio)-4H-chromen-4-one derivatives has been developed. The reaction between o-hydroxy-phenyl-functionalized enaminones and methylsulfinyl derivatives using T3P® gave good yields of chromone thioether derivatives. The reaction proceeds via domino chromone ring construction and C(sp2)–H bond sulfenylation under transition-metal-free conditions. |
| Databáze: | OpenAIRE |
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