Synthesis and characterization of 2H-, 3H- and 4H-azepine: the first observation of the thermal distribution equilibrium of azepines
Autor: | Masaru Kimura, Ryoichi Okuda, Kyosuke Satake, Shiro Morosawa, Yasuyuki Fujiwara, Michiaki Hashimoto, Izumi Watadani, Hideki Okamoto |
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Rok vydání: | 1991 |
Předmět: | |
Zdroj: | Journal of the Chemical Society, Chemical Communications. :1154 |
ISSN: | 0022-4936 |
DOI: | 10.1039/c39910001154 |
Popis: | Demethoxycarbonylation of methyl 2,5,-di-tert-butyl-1H-azepine-1-carboxylate using 1,8-diazabicyclo[5.4.0]undec-7-ene gives exclusively two isomers of 3H-azepine derivatives, while methyl 3,6-di-tert-butyl-1H-azepine-1-carboxylate gives a mixture of 2H-, 3H- and 4H-azepine derivatives under the same conditions because of a 1,5-hydrogen shift in the resulting triene system. |
Databáze: | OpenAIRE |
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