Plasma amino acids in total parenteral nutrition comparison of continuous and cyclic parenteral nutrition
| Autor: | R. Colin, E. Lerebours, B. Hecketsweiler, F. Matray |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Resuscitation Nitrogen balance Nutrition and Dietetics biology business.industry Critical Care and Intensive Care Medicine biology.organism_classification Amino acid Parenteral nutrition Endocrinology chemistry Biochemistry Tasa Internal medicine medicine business Metabolic profile Oral feeding |
| Zdroj: | Clinical Nutrition. 6:143-149 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/0261-5614(87)90048-3 |
| Popis: | Cyclic nocturnal total parenteral nutrition (TPN) is a widely used technique but its metabolic consequences have not been fully investigated. The aim of this work was to investigate the influence of infusion rhythm on the plasma amino-acid profile in 12 subjects. During two successive 7-day periods and in a randomly chosen order, they received either standard continuous TPN (TPN Co ), i.e., 24 h a day or cyclic TPN (TPN Cy ), i.e., between 5 p.m. and 9 a.m. Caloric and nitrogen supplies were identical in both periods. Plasma amino-acids were analysed at 8:30 a.m. and 4:30 p.m. on the last day of each infusion period. In contrast to the stability observed in TPN Co , TPN Cy led to considerable variations of plasma amino-acid concentrations, creating a profile close to that observed in normal oral feeding conditions. Total 24 h urinary amino-acid elimination and the nitrogen balance did not differ between the two types of TPN. These results show that TPN Cy induces a metabolic profile close to physiological conditions. |
| Databáze: | OpenAIRE |
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