Formation of domain structure of erythrocyte membrane in Wistar rat fed with CeCl3 per os

Autor:	Kui Wang, Yi Cheng, Rong-Chang Li, Maozi Liu, Chunli Bai, You Li
Rok vydání:	2000
Předmět:	Erythrocyte membrane Multidisciplinary Biochemistry Chemistry Atomic force microscopy Biophysics Membrane structure Protein particles Membrane surface Protein secondary structure
Zdroj:	Chinese Science Bulletin. 45:426-429
ISSN:	1861-9541 1001-6538
DOI:	10.1007/bf02884943
Popis:	To explore the possibility of absorption of lanthanides via digestive duct and their effects on the membrane structure and permeability of erythrocytes, the fine structure of erythrocyte membrane from Wistar rats, fed for 70 days of daily administrationper os with 20 mg CeCl3/kg weight, was imaged by means of atomic force microscopy and FT-IR deconvolution spectra. The results show that, although the erythrocytes maintain the intact shape, the change of secondary structure, aggregation and crosslinking of the protein particles of membrane surface and the enlarged lipid regions lead to the domain structure formation. This structure might be responsible for the increasing permeability of erythrocyte membrane.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e04b050e3f4494801018f330ef2cef1a https://doi.org/10.1007/bf02884943 Zobrazit plný text záznamu Full text from SpringerLink