Efficacy of VERYL® in the treatment of cattle naturally infected with gastro-intestinal nematodes in Kenya

Autor: N Isaka, C Chevtzoff, J F Collin, P A Lumumba, E O Mungube, A Caruso-Varès, M W Maichomo, J C Njanja, G Pagny, J M Nginyi
Rok vydání: 2019
Předmět:
Zdroj: Tropical Animal Health and Production. 52:1699-1705
ISSN: 1573-7438
0049-4747
Popis: Co-infections caused by trypanosomes and gastro-intestinal nematodes (GINs) compromise cattle productivity and their control requires a holistic approach. The effectiveness of trypanocides and anthelmintics is compromised by increasing resistance. Use of combined chemotherapeutic products for synergy, mainly practiced in human medicine, is gaining importance in livestock. A trial to evaluate efficacy of VERYL®, containing diminazene diaceturate (3.5 mg/kg body weight) and levamisole chloride (5 mg/kg body weight) for the control of GINs in cattle, was conducted at KALRO-VSRI Muguga, Kenya, between June and August 2016. Thirty-eight cattle aged between 6 and 12 months, naturally infected with GINs, were randomly allocated into two groups; a treatment group received VERYL® intra-muscularly at 10 mL/100 kg bwt and a control group which received Veriben® (Diminazene aceturate) at 3.5 mg/kg bwt. Faecal egg counts (FECs), coproculture, packed cell volume (PCV) and local tolerance at the injection site were measured during the study. FECs were comparable between the treatment and control groups at day 0. However, treatment of cattle with VERYL significantly (p
Databáze: OpenAIRE