On-Line Urea Monitoring: A Further Step towards Adequate Dialysis Prescription and Delivery
| Autor: | F. Gastaldon, C. Ronco, Alessandra Brendolan, P. Frisone, S. Zamboni, Carlo Crepaldi, F. Ghiotto, G. La Greca |
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| Rok vydání: | 1995 |
| Předmět: |
High rate
Chromatography 030232 urology & nephrology Biomedical Engineering Medicine (miscellaneous) Bioengineering General Medicine 030204 cardiovascular system & hematology Pharmacology Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Adequate dialysis chemistry Kt/V Urea kinetics Urea Environmental science Potential source Dialysis (biochemistry) Blood drawing |
| Zdroj: | The International Journal of Artificial Organs. 18:534-543 |
| ISSN: | 1724-6040 0391-3988 |
| Popis: | The Aim Of This Study Is To Present A Clinical Experience Carried Out With A New Device Designed To Measure On-Line Urea Nitrogen Concentration In The Effluent Dialysate. The Biostat 1000® Urea Monitor (Baxter Healthcare, Dirfield, Iii, Usa) Was Utilized In The Present Study. The Monitor Is Based On The Principle That Multiple Urea Measurements In The Dialysate Effluent From The Dialyzer, Permit To Built A Double Exponential Regression Leading To The Urea Kinetic Parameters Of The Dialysis Session. Data Obtained With The Urea Monitor Were, In The Present Study, Compared With Those Obtained By Direct Measurements Carried Out In Blood And Dialysate And By The Collection Of The Whole Amount Of Spent Dialysate. The Monitor Provided An Accurate Value Of Predialysis Bun Without Any Blood Drawing. Urea Kinetics Were Established From Multiple Dialysate Measurements And No Blood Drawing Was Necessary. The Double Pool Kinetics Were Taken Into Account And Kt/V, Pcr And Sri° Obtained Were Comparable To Those Obtained From Direct Measurement. Since A Projected Value Of Kt/V Can Be Obtained, The Monitor Could Represent A Potential Source Of Information To Detect Possible Filter And Machine Dysfunction, As Well As High Rate Of Recirculation. |
| Databáze: | OpenAIRE |
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