Dynamics of amino-acid composition of the medium in isolated organ culture by the controlled-perfusion method

Autor: V. P. Nefedov, Barashkov Va, I. I. Gitel'zon, Trubachev In
Rok vydání: 1975
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 80:759-761
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00809881
Popis: The dynamics of the amino-acid composition of the perfusion fluid was investigated during adequate perfusion of isolated dog organs (the thorax and a complex consisting of the thoracic organs, kidneys, and liver). The concentration of amino acids such as histidine, lysine, and alanine in the perfusion fluid 6 h after the beginning of perfusion of the organ complex was higher, whereas that of arginine, serine, aspartic acid, threonine with glutamine, isoleucine, proline, leucine, and valine was much lower than initially. In experiments on the isolated thorax the dynamics of the amino-acid composition of the medium was studied during perfusion for 4 h. The concentration of alanine, lysine, and histidine in the medium increased, whereas those of serine, aspartic acid, isoleucine, tyrosine, and phenylalanine decreased.
Databáze: OpenAIRE