Polyphenolic compounds of a new biologically active extract from immortelle sandy flowers (Helichrysum arenarium (L.) Moench.)
| Autor: | Nikita A. Navolokin, G. N. Maslyakova, N. A. Durnova, Alla B. Bucharskaya, Vyacheslav S. Grinev, Alexander Shirokov, N. V. Polukonova, M. N. Kurchatova |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Naringenin Chromatography biology Organic Chemistry food and beverages 010402 general chemistry biology.organism_classification 01 natural sciences Biochemistry Prunin 0104 chemical sciences 03 medical and health sciences Rutin chemistry.chemical_compound 030104 developmental biology chemistry Polyphenol Helichrysum arenarium Apigenin Quercetin Naringin |
| Zdroj: | Russian Journal of Bioorganic Chemistry. 42:770-776 |
| ISSN: | 1608-330X 1068-1620 |
| DOI: | 10.1134/s1068162016070086 |
| Popis: | The chemical composition of a new bioactive extract from immortelle sandy (Helichrysum arenarium (L.) Moench.) was investigated. Naringin, its soluble aggregate, prunin, quercetin, apigenin, naringenin, apigenin 5-O-glucoside, and isosalipurposide were found among the flavonoids. The tested immortelle sandy extract was shown to contain known dimers, trimers, or more complex aggregates. The compounds had similar spectral but substantially different chromatographic characteristics, which can be used for their identification based on the corresponding data on flavonoids glycosylated at different positions and/or carbohydrates of various complexities, which are also characterized by similar absorption spectra and different retention times. It was found by molecular absorption spectroscopy that the immortelle extract contained 73.48 mg of flavonoids relative to rutin or 17.94 mg relative to quercetin per 1 g of dry extract weight, which corresponded to 20.99 and 5.13%, respectively. The immortelle extract obtained by the method proposed displayed antitumor activity against the transplanted sarcoma 45 and had a beneficial effect on animals in general. |
| Databáze: | OpenAIRE |
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