Chemotactic assay for biological effects of silver nanoparticles

Autor:	E. M. Egorova, S. I. Beilina, V. V. Lednev, N. B. Matveeva
Rok vydání:	2006
Předmět:	Negative chemotaxis fungi Biophysics Nanoparticle Substrate (chemistry) Nanotechnology Physarum polycephalum Chemotaxis Biology biology.organism_classification Silver nanoparticle Slime mold Bacteria
Zdroj:	Biophysics. 51:758-763
ISSN:	1555-6654 0006-3509
DOI:	10.1134/s0006350906050150
Popis:	A method is proposed for assessing the biocidal efficacy of water-dispersed nanoparticles of silver. It is based on negative chemotaxis of the plasmodia of the slime mold Physarum polycephalum. Biocidal and repellent effects were compared for silver nanoparticles, Ag+ ions, and AOT in solution and in the agar gel. In such characteristics as increasing the period of auto-oscillations of contractile activity, decreasing the area of spreading on substrate, and substrate preference in spatial tests, silver nanoparticles proved to be substantially more effective than Ag+ and AOT. The lethal concentrations of the nanoparticles were close to those found earlier for bacteria and viruses. The chemotactic tests allow quantitative assessment of the biological reaction and monitoring its dynamics; in resolution, they are superior to the tests based on the lethal action of biocidal agents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::dfc39113b859b7f80f0e88a7f9c5fe21 https://doi.org/10.1134/s0006350906050150 Zobrazit plný text záznamu Full text from SpringerLink