Cytotoxicity of Mongolian Medicine Aconitum kusnezoffii
| Autor: | Juan Sun, Lijuan Shang, Baofeng Chi, Shiqi Wang, Xiaoyu Gao, Wancheng Zhao, Hairong Zhang, Zhiqiang Li, Xiong Su, Dejun Sun |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Chinese Medicine. 12:10-18 |
| ISSN: | 2151-1926 2151-1918 |
| Popis: | Aconitum kusnezoffii used as an analgesic and anti-inflammatory. It is often used not only in Mongolian medicine but also in traditional Chinese medicine. However, there are few studies on its impact of inflammatory cytokines. This study explored the effects of Aconitum kusnezoffii in vitro used human colon cancer (Caco-2) cells. Cytotoxicity was assessed by measuring effects on expression of IL-1β, IL-6, IL-8, and TNF-α used enzyme-linked immunosorbent assay (ELISA). In vitro study demonstrated that incubation of Caco-2 cells with some kinds of Aconitum kusnezoffii at some concentrations inhibit secretion of TNF-α and FAXIU ACONITUM KUSNEZOFFII could inhibit the secretion of IL-1β. While IL-6 and IL-8 levels were unaffected after 24 h of treatment with Aconitum kusnezoffii, qujian Aconitum kusnezoffii, faxiu Aconitum kusnezoffii. |
| Databáze: | OpenAIRE |
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