Hypertensive disorders in twin pregnancy

Autor: Anca Maria Panaitescu, Gheorghe Peltecu, Radu Botezatu, Nicolae Gică, Anca Marina Ciobanu, Brînduşa Ana Cimpoca-Raptis, Ana Duminică-Turcu, Corina Gică, Pharmacy, Bucharest, Romania
Rok vydání: 2021
Předmět:
Zdroj: Romanian Journal of Medical Practice. 16:32-35
ISSN: 2069-6108
1842-8258
DOI: 10.37897/rjmp.2021.s3.7
Popis: Hypertensive disorders such as gestational hypertension, preeclampsia, eclampsia and HELLP syndrome are one of the most common pregnancy-associated entities that imply substantial maternal-fetal mortality and morbidity. When hypertensive disorders are associated with a multiple pregnancy, the outset is established sooner, with a rapid evolution and a more severe development. Although, the pathophysiology of hypertensive disorders is not fully understood, there are several risk factors that could be identified. A multiple pregnancy implies additional risks due to specific features: larger or multiple placentas, failure of the uteroplacental unit to uphold the natural development of multiple fetuses or elevated risk of abnormal placental site. Hypertensive disorders include complications that are common for both single and multiple pregnancies, complications such as kidney failure, liver dysfunction, neurological or hematological malfunction, among others. Maternal features, including mean arterial blood pressure, uterine artery pulsatility index and blood levels of PAPP-A and/or PlGF could be determined at an early age and used as screening methods.
Databáze: OpenAIRE