An atom efficient, green synthesis of 2-pyrazoline derivatives under solvent-free conditions using grinding technique

Autor: Avinash Shinde, Sainath B. Zangade, Yeshwant B. Vibhute, Shyam S. Mokle
Rok vydání: 2012
Předmět:
Zdroj: Green Chemistry Letters and Reviews. 6:123-127
ISSN: 1751-7192
1751-8253
DOI: 10.1080/17518253.2012.713123
Popis: A simple, rapid, efficient, and environmentally benign procedure for synthesis of 2-pyrazoline derivatives has been achieved by reacting 2′-hydroxychalcones with hydrazine hydrate under solvent-free grinding technique. The short reaction time, cleaner reaction, easy workup, higher yields, and mild reaction conditions make this protocol practical and economically attractive in comparison with the classical reaction.
Databáze: OpenAIRE