An atom efficient, green synthesis of 2-pyrazoline derivatives under solvent-free conditions using grinding technique
Autor: | Avinash Shinde, Sainath B. Zangade, Yeshwant B. Vibhute, Shyam S. Mokle |
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Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Green Chemistry Letters and Reviews. 6:123-127 |
ISSN: | 1751-7192 1751-8253 |
DOI: | 10.1080/17518253.2012.713123 |
Popis: | A simple, rapid, efficient, and environmentally benign procedure for synthesis of 2-pyrazoline derivatives has been achieved by reacting 2′-hydroxychalcones with hydrazine hydrate under solvent-free grinding technique. The short reaction time, cleaner reaction, easy workup, higher yields, and mild reaction conditions make this protocol practical and economically attractive in comparison with the classical reaction. |
Databáze: | OpenAIRE |
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