| Autor: |
M. I. Kabachnik, Tatyana A. Pudova, Godovikov Nn, L. A. Vikhreva |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Phosphorus, Sulfur, and Silicon and the Related Elements. 111:87-87 |
| ISSN: |
1042-6507 |
| DOI: |
10.1080/10426509608054716 |
| Popis: |
We have shown that thioesters of phosphoric acids of general formula (RO)2P(X)C[tbnd]CR1, were X=O or S, containing an acetylenic bond in α-position of the S-ester group has unugually high destructive effect on some isoforms of cytochrome P 450 of arthropods and mammals. These isoforms probably, participate in the process of inactivation of the acetylenic thioesters. We assume that this process may be thought as being a rupture of rhe P-S bond, which leads to the formation of killer particles - alkylthioketenes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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