Levels of plasma B-esterases and glutathione-S-transferase activities in three South American toad species
| Autor: | Paola M. Peltzer, Rafael Carlos Lajmanovich, Mariana C. Cabagna, Andres Maximiliano Attademo, Agustín Bassó, Gabriela S. Fiorenza, Juan C. Sanchez-Hernandez |
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| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
biology Health Toxicology and Mutagenesis Toad Glutathione Pollution chemistry.chemical_compound Carboxylesterase Enzyme Glutathione S-transferase Malaoxon chemistry Biochemistry biology.animal South american biology.protein Environmental Chemistry Butyrylcholinesterase |
| Zdroj: | Toxicological & Environmental Chemistry. 90:1145-1161 |
| ISSN: | 1029-0486 0277-2248 |
| DOI: | 10.1080/02772240801923107 |
| Popis: | We determined the normal levels of butyrylcholinesterase (BChE), carboxylesterase (CbE), and glutathione S-transferases (GST) activities in three South American toad species in order to establish reference values for field pesticide monitoring purposes. Interspecies variations in B-esterase and GST activities were examined according to body mass. In addition, comparative inhibition of BChE and CbE activities using malaoxon, and chemical reactivation of malaoxon-inhibited BChE activity using pyridine-2-aldoxime methochloride (2-PAM) were investigated. Bufo fernandezae had average activity values for BChE: 17.31 mmol min−1 ml−1; CbE: 621.49 nmol min−1 ml−1 and GST: 1.94 mmol min−1 ml−1 while B. arenarum enzymatic average activities were BChE: 9.51 mmol min−1 ml−1; CbE: 270.07 nmol min−1 ml−1, and GST: 1.59 mmol min−1 ml−1; finally Bufo schneideri had enzymatic mean values of BChE: 2.08 mmol min−1 ml−1; CbE: 301.95 nmol min−1 ml−1, and GST: 1.60 mmol min−1 ml−1. Moreover, we found an allometric relationship ... |
| Databáze: | OpenAIRE |
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