Development of a Quantitative Determination Procedure for Polyphenolic Compounds in Medicinal Plant Raw Material and Medicinal Herbal Preparations Using TLC with Stepwise Elution
Autor: | E. F. Safonova, A. I. Slivkin, O. V. Trineeva |
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Rok vydání: | 2019 |
Předmět: |
Pharmacology
chemistry.chemical_classification Chromatography Chemistry media_common.quotation_subject food and beverages Raw material Cosmetics chemistry.chemical_compound Polyphenol visual_art Drug Discovery visual_art.visual_art_medium Tannin Herbal preparations Bark Gallic acid Quercetin media_common |
Zdroj: | Pharmaceutical Chemistry Journal. 52:946-951 |
ISSN: | 1573-9031 0091-150X |
Popis: | A cost-effective and rapid procedure to identify and quantify polyphenolic biologically active compounds of plant origin (with gallic acid, tannin, and quercetin as examples) using high-performance thin-layer chromatography (HPTLC) was developed. The optimal TLC conditions were chosen experimentally and justified theoretically with quantitative interpretation of the HPTLC data on a PC. The proposed method was tested using medicinal plant raw materials such as nettle leaves, common oak bark, and sea buckthorn fruit. The procedure could be used for quality control of drug substances, single-component and complex preparations, plant materials, biologically active additives, premixes, food items, and cosmetics. |
Databáze: | OpenAIRE |
Externí odkaz: | |
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