Synthesis of the potent analgesic compound (±)-epibatidine using an orchestrated multi-step sequence of polymer supported reagents

Autor:	Steven V. Ley, Jörg Habermann, James S. Scott
Rok vydání:	1999
Předmět:	Chemistry Epibatidine medicine Organic chemistry Sequence (biology) Sequestering Agent Polymer supported reagents Combinatorial chemistry medicine.drug
Zdroj:	Journal of the Chemical Society, Perkin Transactions 1. :1253-1256
ISSN:	1364-5463 0300-922X
Popis:	A ten-step synthesis of (±)-epibatidine 1 is described, using an organised array of polymer supported reagents and sequestering agents in a successive manner. No chromatographic purification steps are required to afford the product in >90% purity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::df68b06925b075b0fd514cd4c76f34f4 https://doi.org/10.1039/a901802f Zobrazit plný text záznamu