Aggressive Surgical Management for Metastatic Liver Tumors From Squamous Cell Carcinomas: Report of Three Cases

Autor: Isamu Makino, Jun Kinoshita, Hironori Hayashi, Tetsuo Ohta, Itasu Ninomiya, Hiroyuki Takamura, Keishi Nakamura, Hirohisa Kitagawa, Tomoharu Miyashita, Katsunobu Oyama, Takashi Tani, Sachio Fushida, Hidehiro Tajima, Takashi Fujimura, Shinichi Nakanuma, Hisatoshi Nakagawara
Rok vydání: 2015
Předmět:
Zdroj: International Surgery. 100:1271-1275
ISSN: 2520-2456
0020-8868
DOI: 10.9738/intsurg-d-14-00312.1
Popis: The use of hepatectomy for the treatment of metastatic liver tumors (MLTs) arising from squamous cell carcinomas (SCCs) has not been well investigated. The use of hepatectomy for MLTs from SCCs, especially in advanced cases, needs further investigation. Three patients with SCC-derived MLTs underwent hepatectomy. On clinicopathologic examination, the primary lesions were found to be oral cancer, lung cancer, and oropharyngeal cancer, with synchronous metastasis in 2 patients and metachronous metastasis in 1 patient. One case also involved adrenal metastasis, and another involved direct invasion of the diaphragm and lung. In all cases, surgery was performed to eliminate any residual tumor tissue. After the hepatectomy, 1 patient died (22 months postoperatively) of an unrelated disease, 1 remains alive (30 months postoperatively) with a recurrent tumor, and 1 remains alive (60 months postoperatively) without recurrence. For the patients with solitary MLT derived from SCC, hepatectomy gives a chance for a cure. Thus, aggressive hepatectomy is an important modality in the multidisciplinary approach for controlling SCC-derived MLTs.
Databáze: OpenAIRE