NMR microscopy with a high-resolution liquid-state spectroscopy probe

Autor: Joëlle Amédée, Jean-Michel Franconi, Laurent Pothuaud, Laure De Taillac, Sylvain Miraux, Eric Thiaudière, Paul Canioni, Gérard Raffard
Rok vydání: 2005
Předmět:
Zdroj: Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering. :12-17
ISSN: 1552-5031
DOI: 10.1002/cmr.b.20030
Popis: NMR microscopy is usually achieved at ultra-high-static magnetic field (9.4 Tesla) with the use of home-built coils adapted to the size of the sample. In that way, well-resolved images can be obtained with voxel size smaller than 50 m. The purpose of this article is to show that high-resolution imaging can be realized at lower field strength (4.7 Tesla) using 5- and 10-mm probes initially dedicated to vertical magnets. These coils are easily adaptable to horizontal imaging systems. Excellent quality and filling factors permitted isotro- pic resolutions (50 m) on a biomaterial and on mouse femoris. This study also demonstrates that spoiled-gradient echo sequence (FLASH) with low reception bandwidth or with the use of gadolinium are particularly effective for 3D MR microscopy. © 2005 Wiley Periodicals, Inc.
Databáze: OpenAIRE