NMR microscopy with a high-resolution liquid-state spectroscopy probe
Autor: | Joëlle Amédée, Jean-Michel Franconi, Laurent Pothuaud, Laure De Taillac, Sylvain Miraux, Eric Thiaudière, Paul Canioni, Gérard Raffard |
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Rok vydání: | 2005 |
Předmět: |
Materials science
Radiological and Ultrasound Technology Gadolinium Bandwidth (signal processing) chemistry.chemical_element Nmr microscopy Magnetic field Nuclear magnetic resonance Liquid state chemistry Magnet Microscopy Radiology Nuclear Medicine and imaging Physical and Theoretical Chemistry Spectroscopy |
Zdroj: | Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering. :12-17 |
ISSN: | 1552-5031 |
DOI: | 10.1002/cmr.b.20030 |
Popis: | NMR microscopy is usually achieved at ultra-high-static magnetic field (9.4 Tesla) with the use of home-built coils adapted to the size of the sample. In that way, well-resolved images can be obtained with voxel size smaller than 50 m. The purpose of this article is to show that high-resolution imaging can be realized at lower field strength (4.7 Tesla) using 5- and 10-mm probes initially dedicated to vertical magnets. These coils are easily adaptable to horizontal imaging systems. Excellent quality and filling factors permitted isotro- pic resolutions (50 m) on a biomaterial and on mouse femoris. This study also demonstrates that spoiled-gradient echo sequence (FLASH) with low reception bandwidth or with the use of gadolinium are particularly effective for 3D MR microscopy. © 2005 Wiley Periodicals, Inc. |
Databáze: | OpenAIRE |
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