Effect of Masfon-Aloe vera Drink on Intestinal Motility and Transit in Wistar Albino Rats
| Autor: | Archibong Nsa Archibong, V. O. Oka, DE Ikpi, Ofem Effiong Ofem, AB Antai |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Environmental Engineering Contraction (grammar) biology business.industry medicine.medical_treatment Motility Ileum biology.organism_classification Gastroenterology Industrial and Manufacturing Engineering Aloe vera Intestinal motility Atropine medicine.anatomical_structure Endocrinology Internal medicine medicine business Saline Acetylcholine medicine.drug |
| Zdroj: | British Journal of Medicine and Medical Research. 4:1335-1344 |
| ISSN: | 2231-0614 |
| DOI: | 10.9734/bjmmr/2014/6589 |
| Popis: | The effect of Masfon-Aloe vera drink on intestinal transit and motility was investigated in this study. Thirty (30) albino Wistar rats were divided into 2 batches of 15 rats each, batch 1 for intestinal motility, and batch 2 for intestinal transit experiments. Each batch was further divided into three groups of 5 rats each (control, low dose and high dose). All groups were fed with normal rat chow and water for 21 days. In addition, the control received 0.3 ml of normal saline (0.9% NaCl solution) while the low dose (LD) and high dose (HD) experimental groups received Masfon Aloe vera drink (1 ml and 3 ml/kg body weight orally, once daily respectively). The study was carried out at the Department of Physiology, University of Calabar, Nigeria. At the end of the study duration, intestinal motility and transit studies were conducted. Result for intestinal motility showed the extract (Masfon-Aloe vera drink), at either low or high dose did not significantly change the frequency and amplitude of the spontaneous contraction (basal contraction) of the rat ileum when compared with the control. Graded concentrations of Acetylcholine (10 to 10) was observed to produce a dose dependent increase in contraction of the rat ileum which was significantly (p |
| Databáze: | OpenAIRE |
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