Autor:	Stephen G. Davies, Jeffrey Mckenna, Charles J. R. Hedgecock
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Thienamycin Lithium amide chemistry Stereochemistry Enantioselective synthesis Michael reaction General Medicine Sequence (medicine)
Zdroj:	ChemInform. 27
ISSN:	0931-7597
DOI:	10.1002/chin.199611301
Popis:	Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide.
Databáze:	OpenAIRE
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