Oxidative fragmentation of oxiranes to nitriles with hypervalent iodine(V) reagents in aqueous ammonia

Autor:	Ravindra R. Jadhav, Swapnil S. Deshmukh, Krishnacharya G. Akamanchi, Sameerana N. Huddar
Rok vydání:	2011
Předmět:	Aqueous solution Chemistry Organic Chemistry Hypervalent molecule chemistry.chemical_element Oxidative phosphorylation Iodine Photochemistry Biochemistry Ammonia chemistry.chemical_compound Fragmentation (mass spectrometry) Reagent Drug Discovery Bond cleavage
Zdroj:	Tetrahedron Letters. 52:4533-4536
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2011.06.068
Popis:	Oxiranes undergo oxidative fragmentation when treated with hypervalent iodine(V) reagents particularly o-iodoxybenzoic acid in aqueous ammonia to give nitriles. The reaction goes via the formation of 1, 2-amino alcohols as intermediates followed by C–C bond cleavage.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::df122e3f4321bab15c4d5b91b9acfc6d https://doi.org/10.1016/j.tetlet.2011.06.068 Zobrazit plný text záznamu Full Text from ScienceDirect