Asymmetric hydrogenation of 1-silyl-1-substituted alkenes for preparation of optically active silanes

Autor:	Rui Li, Dan-Dan Ma, Peiming Gu
Rok vydání:	2016
Předmět:	Silanes Silylation 010405 organic chemistry Organic Chemistry Asymmetric hydrogenation Cationic polymerization Noyori asymmetric hydrogenation Optically active 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Yield (chemistry) Drug Discovery Organic chemistry
Zdroj:	Tetrahedron Letters. 57:5666-5668
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2016.11.017
Popis:	Asymmetric hydrogenation of 1-silyl-1-substituted alkenes has been explored, producing eight optically active silanes with good to excellent enantioselectivity (66–99% ee) and yield (74–99%). The reaction was efficiently catalyzed by the cationic N,P-Ir complexes, and the polar solvents were found to be essential for the stereocontrol of the conversion.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::df0b8adbb4960dfa1fab1824a2260a03 https://doi.org/10.1016/j.tetlet.2016.11.017 Zobrazit plný text záznamu Full Text from ScienceDirect